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The Stockwell Laboratory

Identification of a small molecule that induces ATG5-and-cathepsin-l-dependent cell death and modulates polyglutamine toxicity

Identification of essential sites of lipid peroxidation in ferroptosis

Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells

Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries

Identification of Potential Therapeutic Drugs for Huntington's Disease using Caenorhabditis elegans

Identification of simple compounds with microtubule-binding activity that inhibit cancer cell growth with high potency

Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility

Increased erythrophagocytosis induces ferroptosis in red pulp macrophages in a mouse model of transfusion

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Columbia Affiliations

CU DEPARTMENT OF BIOLOGICAL SCIENCES

DEPARTMENT OF CHEMISTRY

Herbert Irving Comprehensive Cancer Center

Irving Institute for Cancer Dynamics

Columbia University Data Science Institute

Center for Motor Neuron Biology and Disease

Precision Medicine Initiative