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The Stockwell Laboratory

Determination of the subcellular localization and mechanism of action of ferrostatins in suppressing ferroptosis

Development of a primary microglia screening assay and its use to characterize inhibition of system xc- by erastin and its analogs

Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents

Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19

Development of small-molecule probes that selectively kill cells induced to express mutant RAS

Development of therapies for rare genetic disorders of GPX4: roadmap and opportunities

Discovery of Anticancer Agents of Diverse Natural Origin

Discovery of Mdm2-MdmX E3 Ligase Inhibitors Using a Cell-Based Ubiquitination Assay

Dr. Hengrui Liu's GPX4 work featured on the cover of ACS Chemical Biology

Drug discovery: Engineering drug combinations

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Columbia Affiliations

CU DEPARTMENT OF BIOLOGICAL SCIENCES

DEPARTMENT OF CHEMISTRY

Herbert Irving Comprehensive Cancer Center

Irving Institute for Cancer Dynamics

Columbia University Data Science Institute

Center for Motor Neuron Biology and Disease

Precision Medicine Initiative