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The Stockwell Laboratory

Regulated necrosis: disease relevance and therapeutic opportunities

Regulation of Ferroptotic Cancer Cell Death by GPX4

Regulation of lipid peroxidation and ferroptosis in diverse species

Researchers Discover That a Rare Fat Molecule Helps Drive Cell Death

Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis

Restoring functions of tumor suppressors with small molecules

Selective inhibitors of death in mutant huntingtin cells

Small Molecule Allosteric inhibitors of GPX4

Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington's disease

Small Molecule Screen Reveals Regulation of Survival Motor Neuron Protein Abundance by Ras Proteins

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Columbia Affiliations

CU DEPARTMENT OF BIOLOGICAL SCIENCES

DEPARTMENT OF CHEMISTRY

Herbert Irving Comprehensive Cancer Center

Irving Institute for Cancer Dynamics

Columbia University Data Science Institute

Center for Motor Neuron Biology and Disease

Precision Medicine Initiative